About 6 results found for searched term "YF2" (0.107 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M5648 | Floxuridine | DNA/RNA Synthesis |
| Deoxyfluorouridine; FDUR; NSC 27640 | ||
| Floxuridine (5-fluorouracil 2'-deoxyriboside) is a pyrimidine analogue that is also an antitumor metabolite of oncology. Floxuridine inhibits the Poly(ADP-Ribose) polymerase and induces DNA damage in vitro by activating ATM and ATR checkpoint signaling pathways. Floxuridine is an effective inhibitor of Staphylococcus aureus infection and can induce apoptosis. Floxuridine is resistant to HSV and CMV viruses. | ||
| M9445 | YF2 | Histone Acetyltransferase |
| YF-2 | ||
| YF2 is a selective HAT (histone acetyltransferase) activator, with EC50 values of 2.75 μM, 29.04 μM and 49.31 μM for CBP, PCAF and GCN5, respectively. | ||
| M17928 | (1β,2β,3β,4β,5β,7α,22α)-27-(β-D-Glucopyranosyloxy)-1,2,3,4,5,7,22-heptahydroxyfurost-25-en-6-one | Others |
| （1β,2β,3β,4β,5β,7α,22α）-27-（β-D-Glucopyranosyloxy）-1,2,3,4,5,7,22-heptahydroxyfurost-25-en-6-one | ||
| M29047 | YF-452 | VEGFR/PDGFR |
| YF-452 is a potent inhibitor of vascular endothelial growth factor receptor 2 (VEGFR2). YF-452 remarkably inhibits the migration, invasion and tube-like structure formation of human umbilical vein endothelial cells (HUVECs) with little toxicity. YF-452 inhibits VEGF-induced phosphorylation of VEGFR2 kinase and the downstream protein kinases including extracellular signal regulated kinase (ERK), focal adhesion kinase (FAK) and Src. YF-452 is a potential antiangiogenic agent candidate for cancer research. | ||
| M39669 | 2-(1-Hydroxy-1-methylethyl)-4-methoxyfuro-[3,2-g]benzopyran-7-one | Others |
| 2-(1-Hydroxy-1-methylethyl)-4-methoxyfuro-[3,2-g]benzopyran-7-one is a compound isolated from sugarcane bagasse. | ||
| M52491 | LPYFD-NH2 | Amyloid |
| LPYFD-NH2, a pentapeptide, exerts some inhibitory effect on the aggregation of Aβ(1-42). | ||
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