About 2 results found for searched term "XL-184" (0.116 seconds)
Cat.No. | Name | Target |
---|---|---|
M1757 | XL-184 | c-Met |
Cabozantinib, BMS-907351,Cabometyx | ||
XL184 is a small molecule inhibits multiple receptor tyrosine kinases, specifically MET and VEGFR2 with IC50 values of 0.035 and 1.8 nM for VEGFR2 and Met respectively. | ||
M4894 | Cabozantinib malate | VEGFR/PDGFR |
XL184;Cabozantinib S-malate | ||
Cabozantinib malate (XL184) is the malate of Cabozantinib, a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM in cell-free assays, respectively. |
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