About 4 results found for searched term "X-376" (0.121 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1743 | X-376 | ALK |
| X-376 is a potent and highly specific ALK small molecule tyrosine kinase inhibitor with IC50 of 0.61 nM. | ||
| M27770 | Nemorubicin | DNA/RNA Synthesis |
| Methoxymorpholinyl doxorubicin; FCE 23762; PNU 152243 | ||
| Nemorubicin (Methoxymorpholinyl doxorubicin) is a Doxorubicin derivative with potent antitumor activity. Nemorubicin is highly cytotoxic to a variety of tumor cell lines presenting a multidrug-resistant phenotype. Nemorubicin not only intercalate into the duplex DNA, but also result in significant ligands for G-quadruplex DNA segments, stabilizing their structure. Nemorubicin requirs an intact nucleotide excision repair (NER) system to exert its activity. | ||
| M5864 | Pazufloxacin mesylate | Antibiotic |
| T-3762; Pazufloxacin methanesulfonate; Pazufloxacin mesilate | ||
| Pazufloxacin (T-3761) mesylate is a fluoroquinolone antibiotic. | ||
| M8624 | HPB | Others |
| HPB is a cell-permeable, non-cytotoxic N-hydroxybenzamide derivative that acts as a HDAC6-selective deacetylase inhibitor (IC50 = 31/376/677/842/1133 nM against HDAC6/8/10/1/7, >2 μM against HDAC2/3/4/11/9/5). | ||
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