WRN inhibitor 1 - Search Results

About 4 results found for searched term "WRN inhibitor 1" (0.277 seconds)

Cat.No.	Name	Target
M41462	WRN inhibitor 1	DNA/RNA Synthesis
	WRN inhibitor 1 is a Wemer Syndrome ATP dependent helicase enzyme (WRN) inhibitor that inhibits WRN helicase domain activity.
M11056	NSC 617145	DNA/RNA Synthesis
	NSC 617145 is a selective werner syndrome helicase (WRN) helicase inhibitor,IC50 The value is 230 nM. NSC 617145 inhibit WRN ATPase and induce double-strand rupture (DSB) and chromosomal abnormalities. NSC 617145 is selective to WRN and superior to BLM, FANCJ, ChlR1, RecQ, and UvrD helicases.
M30527	NCGC00029283	DNA/RNA Synthesis
	NCGC00029283 is a werner syndrome helicase-nuclease (WRN) helicase inhibitor with IC50s of 2.3 μM, 12.5 μM, and 3.4 μM for WRN, BLM and FANCJ helicase, respectively.
M58666	GSK4418959	DNA/RNA Synthesis
	IDE275
	GSK4418959 (IDE275) is a non-covalent, reversible, selective and orally active WRN helicase inhibitor. GSK4418959 inhibits ATPase and DNA unwinding functions in an ATP-competitive manner.