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 About 5 results found for searched term "Vincristine" (0.181 seconds)

Cat.No.  Name Target
M1892 Vincristine sulfate Microtubule
leurocristine, Oncovin
Vincristine, formally known as leurocristine, is a mitotic inhibitor used in cancer chemotherapy.
M4350 Vincristine Anti-infection
Vincristine
M8641 LP117 Others
LP117 is a pirinixic acid derivative that interferes with ATP-binding cassette (ABC) transporter ABCB1-mediated substrates transport, including vincristine, vinorelbine, paclitaxel, and actinomycin D, but not doxorubicin, rhodamine 123, or JC-1.
M28250 SR9186 Cytochrome P450 (e.g. CYP17)
ML368
SR9186 (ML368) is a potent CYP3A4 inhibitor with IC50 s for inhibition of midazolam → 1′hydroxymidazolam, testosterone → 6β-hydroxytestosterone, and vincristine → vincristine M1 of 9, 4, and 38 nM, respectively. SR-9186 inhibits liver-stage development of P. falciparum to block ivermectin metabolism.
M40461 Taxinine Others
Taxinine is a modifier of multidrug resistance in tumor cells. Taxinine can increase cellular accumulation of vincristine in multidrug-resistant cells.



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