About 3 results found for searched term "VX-222" (0.119 seconds)
Cat.No. | Name | Target |
---|---|---|
M2219 | RVX-208 | Epigenetic Reader Domain |
RVX000222; Apabetalone | ||
Apabetalone (RVX-208) is a first-in-class, small molecule inhibitor of BET bromodomain with IC50 of 0.51 μM for BD2. | ||
M3512 | VX-222 | HCV Protease |
VCH-222, Lomibuvir | ||
VX-222 (VCH-222) is a novel, potent and selective inhibitor of HCV polymerase with IC50 of 0.94-1.2 μM, 15.3-fold less effective for mutant M423T, and 108-fold less effective for mutant I482L. | ||
M55976 | Lomibuvir | DNA/RNA Synthesis |
Lomibuvir (VX-222), a selective, non-nucleoside polymerase inhibitor, targets thumb pocket 2 of the HCV NS5B polymerase (RdRp) with a Kd of 17 nM. |
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