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 About 3 results found for searched term "VX-222" (0.119 seconds)

Cat.No.  Name Target
M2219 RVX-208 Epigenetic Reader Domain
RVX000222; Apabetalone
Apabetalone (RVX-208) is a first-in-class, small molecule inhibitor of BET bromodomain with IC50 of 0.51 μM for BD2.
M3512 VX-222 HCV Protease
VCH-222, Lomibuvir
VX-222 (VCH-222) is a novel, potent and selective inhibitor of HCV polymerase with IC50 of 0.94-1.2 μM, 15.3-fold less effective for mutant M423T, and 108-fold less effective for mutant I482L.
M55976 Lomibuvir DNA/RNA Synthesis
Lomibuvir (VX-222), a selective, non-nucleoside polymerase inhibitor, targets thumb pocket 2 of the HCV NS5B polymerase (RdRp) with a Kd of 17 nM.



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