About 1 result found for searched term "VU661013" (0.13 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M21643 | VU661013 | Bcl-2 |
| VU0661013 | ||
| VU661013 is a novel, potent, selective MCL1 inhibitor with Ki of 97 ± 30 pM to human MCL-1 in a TR-FRET assay. VU661013 destabilizes BIM/MCL1 association, leads to apoptosis in AML, and is active in venetoclax-resistant cells and xenografts. | ||
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