About 7 results found for searched term "VDAC" (0.191 seconds)
Cat.No. | Name | Target |
---|---|---|
M2679 | Erastin | Ferroptosis |
Erastin is a ferroptosis activator by acting on mitochondrial VDAC, exhibiting selectivity for tumor cells bearing oncogenic RAS. *The compound is unstable in solutions, freshly prepared is recommended | ||
M7433 | TRO 19622 | Others |
Olesoxime; NSC 21311 | ||
TRO 19622 is a binds voltage-dependent anion channel (VDAC). | ||
M9745 | DIDS sodium salt | VDAC |
MDL101114ZA | ||
DIDS sodium salt (MDL101114ZA) is a dual ABCA1 and VDAC1 inhibitor. DIDS sodium salt is also an anion transport inhibitor, which inhibits the ClC-Ka chloride channel and the bacterial ClC-ec1Cl-/H+ exchanger with IC50s of 100 μM and ~300 μM, respectively. | ||
M10969 | NSC 15364 | Apoptosis |
NSC 15364 is a VDAC1 oligomerization and apoptosis inhibitor. | ||
M11041 | WEHI-9625 | VDAC |
WEHI-9625 is a first-in-class tricyclic sulfone, first-in-class inhibitor of apoptosis with an EC50 of 69 nM. WEHI-9625 binds to VDAC2 and promotes its ability to inhibit apoptosis driven by mouse BAK. WEHI-9625 is completely inactive against both human BAK and the closely related apoptosis effector BAX. | ||
M31410 | Tuvatexib | VDAC |
Tuvatexib is a dual VDAC/HK2 small molecule modulator for studies related to squamous cell carcinoma. | ||
M45387 | VBIT-4 | VDAC |
VBIT-4 is a voltage-dependent anion channel (VDAC1) oligomer inhibitor with a Kd value of 17 μM.In addition, VBIT-4 is an inhibitor of apoptosis and can be used in studies related to neurodegenerative and cardiovascular diseases. |
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