About 3 results found for searched term "Ursodiol" (0.125 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M5158 | Tauroursodeoxycholic acid (Ursodoxicoltaurine) | ERK |
| TUDCA; Ursodoxicoltaurine; Ursodeoxycholyltaurine; Tauroursodeoxycholate; UR 906; Taurursodiol | ||
| Tauroursodeoxycholic acid (Ursodoxicoltaurine) is an endoplasmic reticulum stress inhibitor. It can significantly reduce the expression of apoptotic molecules such as caspase-3 and caspase-12. Tauroursodeoxycholate also suppresses ERK. It is a taurine conjugate of usodeoxycholic acid. | ||
| M6047 | Ursodiol | Animal Modeling |
| UDCA；Ursodeoxycholic acid; UDCS；Ursodeoxycholate; Ursodiol | ||
| Ursodiol reduces cholesterol absorption and is used to dissolve (cholesterol) gallstones with an IC50 of 0.22 μM. Ursodeoxycholic acid (UDCA), which reduces FXR and closes the ACE2 channel. It can be used to construct animal models of cholelithiasis. | ||
| M13985 | Ursodeoxycholic acid sodium | GPCR19/TGR5 |
| Ursodeoxycholate sodium; Ursodiol sodium; UCDA sodium | ||
| Ursodeoxycholic acid (Ursodeoxycholate) sodium is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. | ||
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