About 9 results found for searched term "URAT1 inhibitor 3" (0.14 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M49901 | URAT1 inhibitor 3 | URAT1 |
| URAT1 inhibitor 3 is an orally potent and selective URAT1 inhibitor with an IC50 value of 0.8 nM.URAT1 inhibitor 3 has a uric acid lowering effect and can be used in studies related to gout and hyperuricemia. | ||
| M5734 | Lesinurad | URAT1 |
| RDEA 594, RDEA-594, RDEA594 | ||
| Lesinurad is a URAT1 and OAT inhibitor, is determined to be a substrate for the kidney transporters OAT1 and OAT3 with Km values of 0.85 and 2 µM, respectively. | ||
| M14289 | Lesinurad sodium | URAT1 |
| RDEA-594 sodium | ||
| Lesinurad sodium is a URAT1 and OAT inhibitor, is determined to be a substrate for the kidney transporters OAT1 and OAT3 with Km values of 0.85 and 2 µM, respectively. | ||
| M27919 | Epaminurad | URAT1 |
| UR-1102 | ||
| Epaminurad (UR-1102) is an orally active, potent and selective URAT1 (urate transporter 1) inhibitor, with a Ki of 0.057 μM. Epaminurad quite modestly inhibits OAT1 and OAT3 (organic anion transporter). Epaminurad is a uricosuric agent. Epaminurad can be used for gout and hyperuricemia research. | ||
| M27979 | (Z)-Tyrphostin A51 | EGFR/HER2 |
| (Z)-AG-183 | ||
| (Z)-Tyrphostin A51 is the Z configuration of Lanoconazole A51. Tyrphostin A51 is a potent protein tyrosine kinase (PTK) inhibitor. Tyrphostin A51 inhibits the volume-dependent release of [3H]taurine in a dose-dependent manner. Tyrphostin A51 markedly reduces cellular tyrosyl phosphorylation level. Tyrphostin A51 inhibits both basal and EGF-induced human bone cell proliferation. | ||
| M42269 | URAT1 inhibitor 6 | URAT1 |
| URAT1 inhibitor 6 is a potent URAT1 inhibitor (IC50: 35 nM for hURAT1). | ||
| M42272 | URAT1&XO inhibitor 2 | Xanthine Oxidase |
| URAT1&XO inhibitor 2 is a dual inhibitor of xanthine oxidase and URAT1, with IC50 of 3.3 μM for xanthine oxidase. | ||
| M49902 | URAT1 inhibitor 1 | URAT1 |
| URAT1 inhibitor 1 is a uric acid transporter 1 (URAT1) inhibitor with an IC50 value of 32 nM for inhibition of uric acid transporter 1 (URAT1).It can be used in studies related to hyperuricemia and gout. | ||
| M49905 | KPH2f | URAT1 |
| KPH2f is an orally potent dual URAT1/GLUT9 inhibitor, with IC50s of 0.24 μM and 9.37 μM for URAT1 and GLUT9, respectively.KPH2f had little effect on OAT1 and ABCG2 (IC50s of 32.14 and 26.74 μM, respectively). | ||
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