About 2 results found for searched term "Trimipramine" (0.127 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2796 | Trimipramine Maleate | 5-HT Receptor |
| Trimipramine Maleate is a serotonin transport blocker that also blocks norepinephrine uptake. | ||
| M30561 | Trimipramine | 5-HT Receptor |
| Trimipramine is a 5-HT receptor antagonist, with pKi binding values of 6.39, 8.10, 4.66 for 5-HT1C, 5-HT2 and 5-HT1A, respectively. Trimipramine is also a potent and selective inhibitor targeting human noradrenaline (hNAT), serotonin (hSERT) and organic cation transporters (hOCT1, hOCT2) with IC50 values of 4.99 μM, 2.11 μM, 3.72 μM, 8.00 μM, respectively. Trimipramine has vascular activity and anxiolytic efficacy. | ||
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