About 1 result found for searched term "Teprotumumab" (0.134 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M24540 | Teprotumumab | IGF-1R |
| Teprotumumab is an IGF-1 receptor (IGF-1R) blocking human monoclonal antibody. Teprotumumab binds to the ligand binding extracellular α-subunit domain of IGF-1R. Teprotumumab inhibits TSH and IGF-1 action in fibrocytes. Teprotumumab attenuates TSH-dependent IL-6 and IL-8 expression and Akt phosphorylation. Teprotumumab can be used for thyroid-associated ophthalmopathy research. | ||
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