About 1 result found for searched term "Taminadenant" (0.138 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M28199 | Taminadenant | Adenosine Receptor |
| NIR178; PBF509 | ||
| Taminadenant (NIR178; PBF509) is a highly potent and orally active adenosine A2A receptor (A2AR) antagonist. Taminadenant can antagonize A2AR agonist-mediated cAMP accumulation and impedance responses with KB values of 72.8 nM and 8.2 nM, respectively. Taminadenant reverses motor impairments in several rat models of movement disorders, including catalepsy, tremor, and hemiparkinsonism. | ||
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