About 1 result found for searched term "Talotrexin" (0.129 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M27833 | Talotrexin | Antifolate |
| PT523 | ||
| Talotrexin (PT523), an analog of Aminopterin, is a nonpolyglutamatable classic antifolate. Talotrexin is a RFC (reduced folate carrier) specific inhibitor and selectively inhibits RFC transport. Talotrexin shows antitumor activity by targeting DHFR to inhibit tumor growth. | ||
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