About 1 result found for searched term "TNF-α-IN-2 " (0.171 seconds)
Cat.No. | Name | Target |
---|---|---|
M29166 | TNF-α-IN-2 | TNF Receptor |
TNF-α-IN-2 is a potent and orally active inhibitor of tumor necrosis factor alpha (TNFα), with an IC50 of 25 nM in the HTRF assay. TNF-α-IN-2 distorts the TNFα trimer upon binding, leading to aberrant signaling when the trimer binds to TNFR1. TNF-α-IN-2 can be used for the research of rheumatoid arthritis. |
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