About 8 results found for searched term "TN-16" (0.947 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3789 | ATN-161 TFA | Integrin |
| ATN-161 trifluoroacetate | ||
| ATN-161 TFA salt is a novel small peptide inhibitor of integrin α5β1; a beta integrin antagonist with antitumor activity. | ||
| M8826 | TN-16 | Others |
| Inhibitor of microtubule assembly. | ||
| M29738 | ATN-161 | Integrin |
| ATN-161 is a novel integrin α5β1 antagonist, which inhibits angiogenesis and growth of liver metastases in a murine model. | ||
| M5280 | XMD8-87 | Tyrosinase |
| ACK1-B19 | ||
| XMD8-87 is a novel tyrosine kinase nonreceptor 2(TNK2) inhibitor with IC50s of 38 nmol/L and 113 nmol/L for the D163E and R806Q mutations. | ||
| M5281 | XMD16-5 | Tyrosinase |
| XMD16-5 is a novel tyrosine kinase nonreceptor 2(TNK2) inhibitor with IC50s of 16 nmol/L and 77 nmol/L for the D163E and R806Q mutations. | ||
| M30862 | NSC49652 | Apoptosis |
| NSC49652 is a reversible, orally active p75 neurotrophin receptor (p75NTR, also known as NGFR, TNFRSF16, and CD271) inhibitor. NSC49652 targets the transmembrane domain of p75NTR. NSC49652 induces apoptosis and affects the viability of melanoma cells. | ||
| M45316 | ON 108600 | Casein Kinase |
| ON 108600 is an inhibitor of CK2 (Casein Kinase2)/TNIK/DYRK1 with IC50 values of 0.016 μm/0.007 μM, 0.028 μM, 0.05 μM/0.005 μM, and 0.005 μM for DYRK1A/DYRKB, DYRK2, CK2α1/CK2α2, and TNIK, respectively. 0.005 μM. It has anti-tumor activity. | ||
| M59037 | Estramustine | Microtubule |
| LEO-275 | ||
| Estramustine (LEO-275) is a nitrogen mustard linked to estradiol. Estramustine depolymerizes microtnbules by binding to tubulin 1, exhibits antimitotic activity with an IC50 value of ~16 μM for mitosis of DU 145 cells. Estramustine is selectively taken up by prostate cells and exerts antineoplastic effects by interfering with microtubule of dynamics and by reducing plasma levels of testosterone. | ||
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