About 1 result found for searched term "THIP hydrochloride" (0.151 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M7410 | THIP hydrochloride | GABA Receptor |
| Gaboxadol hydrochloride; Lu 02-030 HCl | ||
| THIP hydrochloride (Gaboxadol hydrochloride) is a potent agonist of the GABAA receptor and an antagonist of GABAC receptors (IC50=25 μM). Gaboxadol hydrochloride displays a partial agonist efficacy on subunit α1β2γ2 with an ED50 value of 143 µM, a full agonist efficacy at α5 subunit (ED50=28-129 µM) and a superagonist efficacy at α4β3δ (ED50=6 µM). | ||
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