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 About 2 results found for searched term "TG101348" (0.123 seconds)

Cat.No.  Name Target
M1733 TG101348 JAK
Fedratinib; SAR302503
TG101348 is a selective small-molecule Janus kinase 2 (JAK2) inhibitor with IC50 of 3 nM.
M28279 Fedratinib hydrochloride hydrate JAK
TG-101348 hydrochloride hydrate; SAR 302503 hydrochloride hydrate
Fedratinib hydrochloride hydrate (TG-101348 hydrochloride hydrate) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor with IC50s of 3 nM for both JAK2 and JAK2V617F kinase. Fedratinib hydrochloride hydrate shows 35- and 334-fold selectivity over JAK1 and JAK3, respectively.



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