About 2 results found for searched term "TG101348" (0.125 seconds)
Cat.No. | Name | Target |
---|---|---|
M1733 | TG101348 | JAK |
Fedratinib; SAR302503 | ||
TG101348 is a selective small-molecule Janus kinase 2 (JAK2) inhibitor with IC50 of 3 nM. | ||
M28279 | Fedratinib hydrochloride hydrate | JAK |
TG-101348 hydrochloride hydrate; SAR 302503 hydrochloride hydrate | ||
Fedratinib hydrochloride hydrate (TG-101348 hydrochloride hydrate) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor with IC50s of 3 nM for both JAK2 and JAK2V617F kinase. Fedratinib hydrochloride hydrate shows 35- and 334-fold selectivity over JAK1 and JAK3, respectively. |
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