About 1 result found for searched term "TAK-242 (Resatorvid)" (0.109 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M4838 | TAK-242 (Resatorvid) | TLR |
| Resatorvid; CLI-095 | ||
| Resatorvid (TAK-242) is a selective TLR4 signaling inhibitor. Resatorvid inhibited the production of NO, TNF-α and IL-6 with IC50 values of 1.8 nM, 1.9 nM and 1.3 nM, respectively. Resatorvid down-regulates the expression of MyD88 and TRIF signaling molecules downstream of TLR4. Resatorvid inhibits autophagy and plays a key role in a variety of inflammatory diseases. | ||
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