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 About 2 results found for searched term "T-5224" (0.329 seconds)

Cat.No.  Name Target
M9373 T-5224 MMP
T-5224 is a transcription factor c-Fos/activator protein (AP)-1 inhibitor with anti-inflammatory effects.
M27770 Nemorubicin DNA/RNA Synthesis
Methoxymorpholinyl doxorubicin; FCE 23762; PNU 152243
Nemorubicin (Methoxymorpholinyl doxorubicin) is a Doxorubicin derivative with potent antitumor activity. Nemorubicin is highly cytotoxic to a variety of tumor cell lines presenting a multidrug-resistant phenotype. Nemorubicin not only intercalate into the duplex DNA, but also result in significant ligands for G-quadruplex DNA segments, stabilizing their structure. Nemorubicin requirs an intact nucleotide excision repair (NER) system to exert its activity.



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