About 2 results found for searched term "SirReal2" (0.129 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M9177 | SirReal2 | Sirtuin |
| SirReal2 is a potent and selective Sirt2 inhibitor with IC50 of 140 nM. | ||
| M29225 | PROTAC Sirt2 Degrader-1 | Sirtuin |
| PROTAC Sirt2 Degrader-1 is a SirReal-based PROTAC, acts as a Sirt2 degrader, composed of a highly potent and isotype-selective Sirt2 inhibitor, a linker, and a bona fide Cereblon ligand for E3 ubiquitin ligase. PROTAC Sirt2 Degrader-1 shows an IC50 of 0.25 μM for Sirt2, with no effect on Sirt1/Sirt3 (IC50s>100 μM). | ||
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