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 About 4 results found for searched term "Senexin B" (0.124 seconds)

Cat.No.  Name Target
M54710 Senexin B CDK
SNX2-1-165; BCD-115
Senexin B is a potent, orally active CDK8/19 inhibitor with Kd values of 140 nM and 80 nM for CDK8 and CDK19, respectively.
M13614 Senexin A CDK
Senexin A is a CDK8 inhibitor with an IC50 of 280 nM.
M29558 Senexin C  CDK
Senexin C is a selective and orally active CDK8/19 inhibitor. Senexin C shows a strong tumor-enrichment pharmacokinetic (PK) profile and tumor-pharmacodynamic (PD) marker responses. Senexin C inhibits the growth of MV4-11 leukemia cells with good tolerability.
M55929 Senexin A hydrochloride  CDK
Senexin A hydrochloride is an inhibitor of CDK8/19 (IC50: 280 nM, CDK8) and an inhibitor downstream of p21 transcription.



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