About 4 results found for searched term "Senexin A" (0.126 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M13614 | Senexin A | CDK |
| Senexin A is a CDK8 inhibitor with an IC50 of 280 nM. | ||
| M55929 | Senexin A hydrochloride | CDK |
| Senexin A hydrochloride is an inhibitor of CDK8/19 (IC50: 280 nM, CDK8) and an inhibitor downstream of p21 transcription. | ||
| M29558 | Senexin C | CDK |
| Senexin C is a selective and orally active CDK8/19 inhibitor. Senexin C shows a strong tumor-enrichment pharmacokinetic (PK) profile and tumor-pharmacodynamic (PD) marker responses. Senexin C inhibits the growth of MV4-11 leukemia cells with good tolerability. | ||
| M54710 | Senexin B | CDK |
| SNX2-1-165; BCD-115 | ||
| Senexin B is a potent, orally active CDK8/19 inhibitor with Kd values of 140 nM and 80 nM for CDK8 and CDK19, respectively. | ||
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