About 1 result found for searched term "SU5416 (Semaxinib)" (0.128 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2031 | SU5416 (Semaxinib) | VEGFR/PDGFR |
| Semaxanib | ||
| Semaxinib (SU5416) is a novel small molecule multi-targeted kinase inhibitor of VEGF receptors, c-kit and FLT3. Semaxinib reversibly inhibits ATP binding to the tyrosine kinase domain of VEGFR2, potentially inhibiting VEGF-stimulated endothelial cell migration and proliferation, thereby reducing tumor microvasculature. | ||
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