About 1 result found for searched term "STAMBP-IN-1 " (0.129 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M30836 | STAMBP-IN-1 | Deubiquitinase |
| STAMBP-IN-1 is a small-molecule inhibitor of STAMBP deubiquitinase, and interrupts STAMBP-Ub-NALP7 interaction. STAMBP-IN-1 decreases protein level of its inflammasome substrate NALP7 and suppresses IL-1b release after Toll-like receptor (TLR) agonism. STAMBP-IN-1 inhibits the activity of STAMBP to cleave recombinant di-Ub with an IC50 value of 0.33 mM. | ||
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