About 9 results found for searched term "ST-193" (0.121 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M7334 | ST 1936 oxalate | Others |
| ST 1936 oxalate is a selective, high affinity 5-HT 6 agonist. | ||
| M9106 | ST-193 | Anti-infection |
| ST193 | ||
| ST-193 is a potent broad-spectrum arenavirus inhibitor; inhibits Guanarito, Junin, Lassa and Machupo virus with IC50 values of 0.44, 0.62, 1.4 and 3.1 nM, respectively. | ||
| M4585 | Taxifolin (TFN) | Autophagy |
| Dihydroquercetin; Taxifoliol; (+)-Dihydroquercetin; (+)-Taxifolin | ||
| Taxifolin (TFN) is an important natural compound with antifibrotic activity. Taxifolin is a free radical scavenger with antioxidant capacity. Taxifolin ((+)-Dihydroquercetin) exhibits important anti-tyrosinase activity. Taxifolin exhibits significant inhibitory activity against collagenase with an IC50 value of 193.3 μM. | ||
| M7128 | PG 01 | CFTR |
| PG 01 is a potent CFTR Cl- channel potentiator.PG01 was effective against E193K, G970R and G551D (CFTR mutants) with Kd values of 0.22 μM, 0.45 μM and 1.94 μM, respectively.PG01 was also effective against ΔF508 (Ka 0.3 μM).PG01 increased ΔF508-CFTR Cl- currents with the addition of Forskolin. F508-CFTR Cl- current after the addition of Forskolin. | ||
| M10625 | GSK2193874 | TRP Channel |
| GSK-2193874; GSK2193874A | ||
| GSK2193874 is a first-in-class orally bioavailable potent antagonist of TRPV4 channels, blocking the influx of calcium induced by the TRPV4 agonist with IC50 values of 2, 5, and 40 nM. GSK2193874 is the first-in-class orally bioavailable TRPV4 inhibitor that demonstrated ability to improve pulmonary functions in a number of heart failure models. | ||
| M10940 | LY2562175 | Farnesoid X Receptor |
| TERN-101 | ||
| LY2562175 is an effective and selective FXR agonist EC50 The value is 193 nM. | ||
| M21096 | TXA6101 | Others |
| TXA6101 is a filamentous temperature-sensitive mutant Z (FtsZ) protein inhibitor. TXA6101 has an antibacterial activity MIC value of 1 μg/mL against MRSA isolates expressing either G193D or G196S mutant FtsZ, retaining significant activity against the TXA707-resistant FtsZ mutant. It is being developed for use against Gram-negative bacteria. | ||
| M21666 | Recombinant Mouse IL-18BPd (HEK293, C-Fc) | Cytokines and Growth Factors |
| Interleukin-18 Binding Protein Isoform d | ||
| Recombinant Mouse Interleukin 18 binding protein (IL-18BP) is a physiological inhibitor that acts through binding to the receptor-binding site of IL-18. Recombinant Mouse Interleukin-18 Binding Protein Isoform d is produced by our Mammalian expression system and the target gene encoding Thr29-Ala193 is expressed with a human IgG1 Fc tag at the C-terminus. | ||
| M50219 | AMG-193 | PRMTs |
| AMG193; PRMT5-IN-27 | ||
| AMG-193 is an orally active inhibitor of the PRMT5/MTA complex for studies related to solid tumors. AMG-193 (PRMT5-IN-27) inhibits HCT116 cell proliferation with an IC 50 of 0.13 μM. | ||
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