About 1 result found for searched term "SS47 " (0.123 seconds)
Cat.No. | Name | Target |
---|---|---|
M29744 | SS47 | PROTAC |
SS47, a PROTAC-based HPK1 degrader, exerts proteasome-mediated HPK1 degradation. The degradation of HPK1 via SS47 also significantly enhances the?in?vivo?antitumor efficacy of BCMA CAR-T cell research. HPK1, an?immunosuppressive?regulatory kinase, is a promising target for cancer immunotherapies. |
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