About 1 result found for searched term "SR-4995" (0.15 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M58498 | SR-4995 | Metabolite/Endogenous Metabolite |
| CID 16016685 | ||
| SR-4995 is a potent and selective ligand of α-β-hydrolase domain containing 5 (ABHD5) that activates adipose triglyceride lipase (ATGL) by dissociating ABHD5 from its inhibitory regulator, perilipin-1 (PLIN1) and PLIN5. SR-4995 directly binds to ABHD5 and prevents ABHD5 to PLIN1. SR-4995 induces lipolysis in adipocytes and muscle, avoiding PKA-dependent signaling. | ||
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