About 1 result found for searched term "SHP2-IN-8 " (0.13 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M28880 | SHP2-IN-8 | Phosphatase |
| SHP2-IN-8 is a highly potent, selective, and cellularly active allosteric SHP2 inhibitor with IC50 value of 23 nM and Ki of 22 nM. SHP2-IN-8 is reversible and noncompetitive. SHP2-IN-8 causes a significant thermal shift with the ΔTm of 7.01 ℃. SHP2-IN-8 induces the apoptosis and inhibits the phosphorylation of AKT in Hela cells. | ||
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