About 9 results found for searched term "SC-43" (0.229 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3745 | TCS PIM-1 1 | Pim |
| SC 204330 | ||
| TCS PIM-1 1 is a potent and selective ATP-competitive Pim-1 kianse inhibitor with IC50 of 50 nM, displays good selectivity over Pim-2 and MEK1/MEK2(IC50s > 20,000 nM). | ||
| M5298 | NSC-144303 | Apoptosis |
| Ubiquitin Isopeptidase Inhibitor I, G5 | ||
| Ubiquitin Isopeptidase Inhibitor I, G5 (NSC-144303) is a broad-spectrum cell-permeable deubiquitinating enzyme (DUB) inhibitor that affects type I IFNs and NF-κB induced by poly(I:C).*The compound is unstable in solutions, freshly prepared is recommended | ||
| M7944 | NSC43067 | Others |
| NSC43067 is a Cyclin-dependent kinase (Cdk) inhibitor which binds to a novel conserved site on Cdk, presumably the p27 binding pocket. | ||
| M9712 | Pyrocatechuic acid | Metabolite/Endogenous Metabolite |
| 2,3-Dihydroxybenzoic acid; Catecholcarboxylic acid; NSC 27435 | ||
| Pyrocatechuic acid (2,3-Dihydroxybenzoic acid) is a normal human benzoic acid metabolite found in plasma, and has increased levels after aspirin ingestion. | ||
| M9948 | SC-43 | Phosphatase |
| SC43 | ||
| SC-43 is a sorafenib derivative, it is a potent and orally active SHP-1 (PTPN6) agonist with anti-tumor activity. | ||
| M21415 | Trabectedin | ROS |
| Ecteinascidin 743; ET-743 | ||
| Trabectedin (Ecteinascidin 743; ET-743) is a tetrahydroisoquinoline alkaloid that binds to the minor groove of DNA, blocks stress-induced transcription of proteins, induces DNA backbone cleavage and apoptosis, and increases ROS production in MCF-7 and MDA-MB-453 cells. Trabectedin can be used in soft tissue sarcoma and ovarian cancer studies. | ||
| M21853 | Aszonalenin | Others |
| NSC 374337 | ||
| Aszonalenin | ||
| M29645 | MSC-4381 | Monocarboxylate Transporter (MCT) |
| MCT4-IN-1 | ||
| MSC-4381 (MCT4-IN-1) is an orally active and selective monocarboxylate transporter 4 (MCT4/SLC16A3) inhibitor with an IC50 of 77 nM and a Ki of 11 nM. MSC-4381 targets to the cytosolic domain of MCT4. MSC-4381 results in lactate efflux inhibition and reduction of cellular viability in MCT4 high expressing cells. MSC-4381 has the potential for MCT4 transporter inhibition research. | ||
| M30346 | NSC243928 mesylate | Others |
| NSC243928 mesylate is a human lymphocyte antigen 6 (LY6) binder, which also acts as an inhibitor of cell growth and has anticancer activity. | ||
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