About 4 results found for searched term "SB203580" (0.126 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1781 | Adezmapimod (SB203580) | p38 MAPK |
| RWJ 64809; PB 203580; Adezmapimod | ||
| Adezmapimod (SB203580) is a P38 MAPK inhibitor with an IC50 of 0.3-0.5 μM, which is 10 times less selective than SAPK3(106T) and SAPK4(106T), and inhibits PKB phosphorylation with an IC50 of 3-5 μM. | ||
| M7249 | SB 203580 hydrochloride | p38 MAPK |
| Adezmapimod hydrochloride ; RWJ 64809 hydrochloride | ||
| SB 203580 hydrochloride is a selective inhibitor of p38 MAPK; water-soluble. | ||
| M7582 | SB 239063 | p38 MAPK |
| SB 239063 is a potent and selective p38 MAPK inhibitor (IC50 = 44 nM for p38α). SB 239063 displays > 220-fold selectivity over ERK, JNK1 and other kinases; ~ 3-fold more selective than SB 203580. | ||
| M28837 | SB 202474 | Others |
| SB 202474, a negative analog of SB203580. SB 202474, which has no ability to inhibit p38 MAPK activity and is widely used as a negative control compound in p38 MAPK studies, also suppressed melanin synthesis induction. | ||
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