About 1 result found for searched term "SB-267268 " (0.079 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M29147 | SB-267268 | Integrin |
| SB-267268 is a selective and nonpeptidic alpha(v)beta3 (αvβ3) and alpha(v)beta5 (αvβ5) integrins antagonist, with Kis of 0.9, 0.5 and 0.7 nM for human αvβ3, monkey αvβ3 and human αvβ5, respectively. SB-267268 inhibits human and mouse αvβ3 with IC50s of 0.68 and 0.29 nM, respectively. SB-267268 reduces angiogenesis and VEGF expression. | ||
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