About 1 result found for searched term "Recombinant Human RIPK3 Protein (E. coli, N-His)" (0.446 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M58110 | Recombinant Human RIPK3 Protein (E. coli, N-His) | Cytokines and Growth Factors |
| RIP-like protein kinase 3; RIP3 | ||
| RIPK3 is a kinase that controls necroptosis and apoptosis. In necroptosis, activated by TNF-α and ZBP1, RIPK3 phosphorylates MLKL, leading to membrane damage. Necroptosis is dependent on receptor-interacting protein kinase 3 (RIPK3), a protein shown to play an important role in experimental models of critical illness. RIPK3 promotes kidney tubular injury via mitochondrial dysfunction. The FAO-dependent RIPK3 mediates pathogenesis of acute lung injury. | ||
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