ROC-325 - Search Results | AbMole BioScience

About 6 results found for searched term "ROC-325" (0.135 seconds)

Cat.No.	Name	Target
M6260	ROC-325	Autophagy
	ROC-325 is an orally available novel inhibitor of lysosomal-mediated autophagy which diminishes AML cell viability with the IC50 range of 0.7-2.2 μM.
M14642	2'-Deoxycytidine hydrochloride	Metabolite/Endogenous Metabolite
	2'-Deoxycytidine monohydrochloride; Deoxycytidine hydrochloride; NSC 83251
	2'-Deoxycytidine hydrochloride is composed of the purine nucleoside guanine linked by its N9 nitrogen to the C1 carbon of deoxyribose.
M28819	AG-1478 hydrochloride	EGFR/HER2
	Tyrphostin AG-1478 hydrochloride; NSC 693255 hydrochloride
	AG-1478 hydrochloride (Tyrphostin AG-1478 hydrochloride) is a selective EGFR tyrosine kinase inhibitor with IC50 of 3 nM. AG-1478 hydrochloride has antiviral effects against HCV and encephalomyocarditis virus (EMCV).
M13956	Aprocitentan	Endothelin Receptor
	ACT-132577
	Aprocitentan (ACT-132577) is the major and pharmacologically active metabolite of Macitentan. Aprocitentan is dual ETA/ETB antagonist with IC50s of 3.4 nM and 987 nM, and pA₂ valus of 6.7 and 5.5, respectively.
M49536	Rho-Kinase-IN-1	ROCK
	Rho-Kinase-IN-1 is a Rho kinase (ROCK) inhibitor (Ki values of 30.5 and 3.9 nM for ROCK1 and ROCK2, respectively) extracted from US20090325960A1, compound 1.008.
M56713	Mepazine hydrochloride	MALT1
	Mepazine hydrochloride (Pecazine hydrochloride) is a potent and selective MALT1 protease inhibitor with IC50s of 0.83 and 0.42 μM for GSTMALT1 full length and GSTMALT1 325-760, respectively.