About 17 results found for searched term "RITA" (0.054 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2578 | RITA | p53 |
| NSC 652287 | ||
| RITA (NSC 652287) is a MDM2 inhibitor and DNA damage agent for A498 (wild type) and TK-10 (mutation) cell lines with a GI50 of 17 nM and 32 nM, respectively. | ||
| M4885 | Oritavancin | Anti-infection |
| LY333328 | ||
| Oritavancin is a Lipoglycopeptide Antibacterial. The mechanism of action of oritavancin is as a Cytochrome P450 2C19 Inhibitor, Cytochrome P450 2C9 Inhibitor, Cytochrome P450 3A4 Inducer, and Cytochrome P450 2D6 Inducer. The chemical classification of oritavancin is Lipoglycopeptides. | ||
| M6133 | Oritavancin diphosphate | Antibiotic |
| LY 333328 diphosphate | ||
| Oritavancin is approved for the treatment of adult patients with acute bacterial skin and skin structure infections (SSSIs) caused by or suspected to be caused by susceptible isolates of designated gram-positive microorganisms. | ||
| M6287 | GLPG1690 | PDE |
| Ziritaxestat | ||
| GLPG1690 (Ziritaxestat) is a first-in-class autotaxin (ATX) inhibitor, with IC50 of 131 nM and Ki of 15 nM. | ||
| M7196 | Ritanserin | Others |
| Ritanserin is a potent 5-HT 2 antagonist. | ||
| M8880 | Paritaprevir | HCV Protease |
| ABT-450 | ||
| Paritaprevir (ABT-450) is a potent non-structural protein 3/4A (NS3/4A) protease inhibitor with EC50 values of 1 and 0.21 nM for HCV 1a and 1b, respectively. | ||
| M14598 | Inulicin | NF-κB |
| 1-O-Acetylbritannilactone | ||
| Inulicin (1-O-Acetylbritannilactone) is an active compound that inhibits VEGF-mediated activation of Src and FAK. | ||
| M17533 | Britannilactone | Sesquiterpenoids |
| Britannilactone | ||
| M17597 | Britanin | Sesquiterpenoids |
| Britanin | ||
| M18926 | Peritassine A | Others |
| Peritassine A | ||
| M25044 | Zuberitamab | CD20 |
| HS006 | ||
| Zuberitamab (HS006) is a monoclonal antibody that targets CD20 and can be used in cancer research, including diffuse large B-cell lymphoma. | ||
| M31386 | Epcoritamab | CD20 |
| Epcoritamab is a novel bispecific IgG1k/λ antibody targeting CD3 and CD20 that activates T cells and directs them to kill malignant CD20+ B cells.Epcoritamab has antitumor activity and may be used in studies related to RR diffuse large B-cell lymphoma (DLBCL). | ||
| M38980 | Britannilactone diacetate | NO Synthase |
| Britannilactone diacetate exhibits activity against NO production induced by LPS in BV-2 microglial cells with the EC50 value of 6.3 μM. Britannilactone diacetate exhibits a favorable blood-brain barriers (BBB) penetration and absorption, distribution, metabolism, excretion, and toxicity (ADMET) property. | ||
| M40365 | Neritaloside | Others |
| Neritaloside could be isolated from nerium oleander. Neritaloside has central nervous system (CNS) depressant effect. | ||
| M44040 | 1-O-Acetyl britannilactone | Others |
| 1-O-Acetyl britannilactone | ||
| M44946 | Neobritannilactone B | Others |
| Neobritannilactone B, a sesquiterpene, can be isolated from the chloroform fraction of the I. britannica. | ||
| M49694 | 6-O-Isobutyrylbritannilactone | ERK |
| 6-O-Isobutyrylbritannilactone is a natural melanogenesis inhibitor. | ||
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