About 4 results found for searched term "RIPK1-IN-7" (0.255 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M21564 | RIPK1-IN-7 | RIPK |
| Ripk1-in-7 is a receptor interacting protein kinase 1 (RIPK1) inhibitor with Kd value of 4 nM and IC50 value of 11 nM. RIPK1-IN-7 showed good antimetastatic activity in experimental B16 melanoma lung metastasis model. | ||
| M5209 | GSK481 | RIPK |
| GSK481 is a highly effective, selective and specific RIPK1 inhibitor with an IC50 value of 1.3 nM, which can inhibit the phosphorylation of Ser166 in wild-type human RIPK1 (IC50 value of 2.8 nM). The IC50 value of GSK481 against U937 cells was 10 nM. | ||
| M13405 | RIPK3-IN-1 | RIPK |
| RIPK3-IN-1 is a RIPK3 TYPE II DFG-out inhibitor with IC50 of 9.1 nM. RIPK3-IN-1 inhibited ABL, BRAF/V599E, MAP4K3 and SRC with IC50 values of 0.37, 0.15, 0.012 and 0.075 μM, respectively. | ||
| M41365 | RIPK2/3-IN-1 | RIPK |
| RIPK2/3-IN-1 is a potent dual RIPK2/3 kinases inhibitor with IC50 values of 3 nM and 117 nM, respectively. | ||
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