About 6 results found for searched term "RI-962" (0.173 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M49365 | RI-962 | RIPK |
| RI-962 is a potent and selective receptor-interacting protein kinase 1 (RIPK1) inhibitor with an IC50 value of 35.0 nM.RI-962 can be used in studies related to neurological disorders and inflammatory diseases. | ||
| M11041 | WEHI-9625 | VDAC |
| WEHI-9625 is a first-in-class tricyclic sulfone, first-in-class inhibitor of apoptosis with an EC50 of 69 nM. WEHI-9625 binds to VDAC2 and promotes its ability to inhibit apoptosis driven by mouse BAK. WEHI-9625 is completely inactive against both human BAK and the closely related apoptosis effector BAX. | ||
| M14020 | Camicinal hydrochloride | Others |
| GSK962040 hydrochloride | ||
| Camicinal hydrochloride (GSK962040 hydrochloride) is a small molecule, selective motilin receptor agonist with pEC50 of 7.9. | ||
| M24696 | Ascrinvacumab | ALK |
| Anti-ACVRL1/ALK-1 Reference Antibody; PF-03446962 | ||
| Ascrinvacumab (PF-03446962) is a human IgG2 monoclonal antibody targets ALK-1. Ascrinvacumab shows binding efficiency with human ALK1 with a Kd value of 7 nM. Ascrinvacumab can be used for the research of hepatocellular carcinoma (HCC). | ||
| M28388 | BI-9627 hydrochloride | Na+/H+ Exchanger (NHE) |
| BI-9627 hydrochloride is potent sodium-hydrogen exchanger isoform 1 (NHE1) inhibitor, with IC50s of 6 and 31 nM in intracellular pH recovery (pHi) and human platelet swelling assays, respectively. BI-9627 hydrochloride displays >30-fold selectivity against NHE2 and with no measurable inhibitory activity against the NHE3 isoform. BI-9627 hydrochloride shows low DDI (agent-agent interaction) potential, excellent pharmacokinetics in rat and dog, and remarkably potent activity in the isolated heart model of ischemia-reperfusion injury. | ||
| M49533 | GSK269962A hydrochloride | ROCK |
| GSK269962A hydrochloride (GSK 269962 hydrochloride) is a potent ROCK inhibitor with IC50s of 1.6 and 4 nM for recombinant human ROCK1 and ROCK2 respectively. | ||
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
