About 2 results found for searched term "RG7800" (0.13 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M11535 | RG7800 | DNA/RNA Synthesis |
| RG-7800; RG 7800; RO6885247; RO-6885247; RO 6885247 | ||
| RG7800 is a small molecule SMN2 splicing modifier. RG7800 has the potential to be used in spinal muscular atrophy. RG7800 corrects selective splicing of the human SMN2 gene in the brain of a transgenic SMA model mouse, leading to an increase in SMN protein in the brain. | ||
| M13653 | RG7800 hydrochloride | DNA/RNA Synthesis |
| RO6885247 hydrochloride | ||
| RG7800 hydrochloride is an orally active SMN2 splicing modulator, with EC1.5xs of 23 nM and 87 nM for SMN2 splicing and SMN protein; RG7800 hydrochloride has the potential to treat spinal muscular atrophy. | ||
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