Polyphyllin-I - Search Results

About 5 results found for searched term "Polyphyllin-I" (0.121 seconds)

Cat.No.	Name	Target
M4361	Polyphyllin-I	JNK
	Polyphyllin I is a bioactive ingredient extracted from Paris Polyphylla with strong anti-tumor activity. Polyphyllin I is an activator of the JNK signaling pathway and an inhibitor of PDK1/Akt/mTOR signaling. Polyphyllin I induces autophagy, G2/M phase arrest and apoptosis.
M4362	Polyphyllin-II	Apoptosis
	Polyphyllin II is one of the most important saponins in Polyphyllin, which has toxic effects on a variety of cancer cells. Polyphyllin II induces apoptosis through caspases activation and cell cycle arrest.
M4363	Polyphyllin-VI	Pyroptosis
	Polyphyllin VI, an active saponin, has anticancer activity. Polyphyllin VI induces G2/M cell cycle arrest and induces apoptosis. Polyphyllin VI induces caspase-1-mediated pyroptosis by inducing ROS/NF-κB/NLRP3/GSDMD signaling axis in non-small cell lung cancer.
M40045	Polyphyllin F	Others
	Polyphyllin F is a diosgenyl saponin that can be found in Paris polyphylla.
M44987	Polyphyllin G	Apoptosis
	Polyphyllin G is isolated from the rhizomes of Paris yunnanensis, with antimicrobial and anticancer activity.