About 2 results found for searched term "Pirfenidone" (0.126 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2328 | Pirfenidone | TGF-beta/Smad |
| AMR69; S-7701 | ||
| Pirfenidone (AMR69) is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells. Pirfenidone inhibits TGF-β bioactivity by affecting TGF-β2 mRNA expression and processing of pro-TGF-β in CCL-64 cells. Pirfenidone (AMR69) attenuates CCL2 and CCL12 production in fibrocyte cells. | ||
| M50178 | GDC-3280 | Others |
| AK3280 | ||
| GDC-3280 is an orally active, potentially best-in-class (BIC) compound further optimized from the chemical structure of pirfenidone for use in studies related to idiopathic pulmonary fibrosis (IPF). | ||
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