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 About 4 results found for searched term "PT-179" (0.138 seconds)

Cat.No.  Name Target
M55581 PT-179 Ligand for E3 Ligase
PT179
PT-179 is an orthogonal Thalidomide (M2225) derivative that targets cereblon without causing off-target degradation effects. PT-179 is able to specifically bind CRBN, form a ternary complex with a target protein fused to a zinc finger (ZF) degron, and mediate the degradation of the tagged protein.
M6087 LXR-623 Liver X Receptor
WAY-252623
LXR-623 is a novel liver X-receptor(LXR) agonist with IC50 values of 179 nM and 24 nM for LXR-α and LXR-β, respectively. It is orally bioavailable and readily passes the blood-brain barrier.
M9695 Ellipticine hydrochloride Topoisomerase
NSC71795 hydrochloride
Ellipticine (NSC 71795) hydrochloride is a potent antineoplastic agent which inhibits DNA topoisomerase II activities.
M28214 UNC10217938A  Others
UNC10217938A is a 3-deazapteridine analog with strong oligonucleotide enhancing effects. UNC10217938A enhances oligonucleotides effects by modulating their intracellular trafficking and release from endosomes. UNC10217938A also enhances the effects of antisense and siRNA oligonucleotides.



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