About 4 results found for searched term "PRMT4-IN-1" (0.127 seconds)
Cat.No. | Name | Target |
---|---|---|
M41695 | PRMT4-IN-1 | Histone Methyltransferase |
PRMT4-IN-1 is a selective inhibitor of PRMT4 (IC50=3.2 nM). | ||
M11055 | TP-064 | PRMTs |
TP-064 is a potent and selective PRMT4 small molecule inhibitor with ic50 < 10 nM, which is more than 100 times more selective for PRMT4 than other PRMT. | ||
M21394 | GSK3368715 3HCl | Others |
GSK3368715 is a potent inhibitor of type I protein arginine methyltransferases (PRMT) that inhibits PRMT1, 3, 4, 6 and 8, corresponding to Kiapp values ranging from 1.5 nM to 81 nM. | ||
M58581 | MS4322 | PROTAC |
YS43-22 | ||
MS4322 (YS43-22) is a specific PRMT5 PROTAC degrader. MS4322 reduces the PRMT5 protein level with a DC50 of 1.1 μM in MCF-7 cells. MS4322 inhibits the methyltransferase activity of PRMT5 with an IC50 of 18 nM. MS4322 promotes ubiquitination and degradation of PRMT5. |
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