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 About 1 result found for searched term "PLN-1474" (0.421 seconds)

Cat.No.  Name Target
M45153 PLN-1474 Integrin
PLN-1474 is an orally active, selective ανβ1 integrin inhibitor with an IC50 value of <50 nM.PLN-1474 significantly reduces hepatic pSMAD3/SMAD3 levels, hepatic collagen gene expression, and hepatic OHP concentration in a mouse model of liver fibrosis. It can be used in studies related to liver cirrhosis and fibrosis.



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