About 4 results found for searched term "PI3Kδ-IN-12" (0.141 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M43393 | PI3Kδ-IN-12 | PI3K |
| PI3Kδ-IN-12 is a PI3Kδ inhibitor (pIC50 = 5.8), with pKi values of 8.0/6.5/6.4/6.7 for PI3Kδ/γ/β/α, respectively. | ||
| M3880 | Acalisib | PI3K |
| GS-9820 | ||
| Acalisib (GS-9820) is a potent and selective PI3Kδ inhibitor with an IC50 of 12.7 nM, with potential immunomodulating and antineoplastic activities. | ||
| M10157 | Seletalisib | PI3K |
| UCB5857 | ||
| Seletalisib (UCB5857) is a potent and selective PI3Kδ inhibitor, with IC50 of 12 nM. | ||
| M14858 | Umbralisib hydrochloride | PI3K |
| TGR-1202 hydrochloride; RP5264 hydrochloride | ||
| Umbralisib hydrochloride (TGR-1202 hydrochloride) is a novel PI3Kδ inhibitor, with IC50 and EC50 of 22.2 nM and 24.3 nM, respectively; Umbralisib hydrochloride (TGR-1202 hydrochloride) is also active against CK1ε, with an EC50 value of 6.0 μM. | ||
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