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 About 8 results found for searched term "PHGDH" (0.126 seconds)

Cat.No.  Name Target
M29015 PHGDH-inactive  PHGDH
PHGDH-inactive has no activity against PHGDH and serves as a negative control of NCT-502 and NCT-503.
M6566 CBR 5884 PHGDH
CBR 5884 is a 3-Phosphoglycerate dehydrogenase (PHGDH) inhibitor.
M8604 NCT-503 PHGDH
NCT-503 is an inhibitor of phosphoglycerate dehydrogenase (PHGDH), which catalyzes the first, rate-limiting step of glucose-derived serine synthesis.
M8753 PKUMDL-WQ-2201 Others
PKUMDL-WQ-2201 is a potent and selective non-NAD+-competing allosteric inhibitor of phosphoglycerate dehydrogenase (PHGDH) that selectively inhibits serine synthesis in cancer cells.
M14660 BI-4916 PHGDH
BI-4916 is a prodrug of BI-4924. BI-4924 is a NADH/NAD+-competitive PHGDH inhibitor.
M14661 BI-4924 PHGDH
BI-4924 is a lipophilic, highly plasma protein bound selective phosphoglycerate dehydrogenase (PHGDH) inhibitor (IC50=3 nM) with excellent microsomal, as well as hepatocytic stability.
M14738 NCT-502 PHGDH
NCT-502 is a human phosphoglycerate dehydrogenase (PHGDH) inhibitor, cytotoxic to PHGDH-dependent cancer cells, and reduces glucose-derived serine production, with an IC50 of 3.7 μM against PHGDH.
M29874 PKUMDL-WQ-2101  PHGDH
PKUMDL-WQ-2101 is a non-NAD+-competing allosteric phosphoglycerate dehydrogenase (PHGDH) inhibitor with an IC50 of 34.8 μM. PKUMDL-WQ-2101 exhibits antitumor activity.

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