About 8 results found for searched term "PFKFB3" (0.123 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M6479 | AZ PFKFB3 26 | PFKFB3 |
| AZ PFKFB3 26 is a potent and selective PFKFB3 inhibitor. | ||
| M28820 | AZ-PFKFB3-67 | PFKFB3 |
| AZ-PFKFB3-67 is potent and selective metabolic kinase PFKFB3 inhibitor, with IC50s of 11, 159 and 1130 nM for PFKFB3, PFKFB2 and PFKFB1 respectively. | ||
| M31070 | AZ-PFKFB3-67 quarterhydrate | PFKFB3 |
| AZ-PFKFB3-67 quarterhydrate is potent and selective metabolic kinase PFKFB3 inhibitor, with IC50s of 11, 159 and 1130 nM for PFKFB3, PFKFB2 and PFKFB1 respectively. | ||
| M4913 | PFK15 | PFKFB3 |
| PFK-015 | ||
| PFK15 is a potent and selective 6-phosphofructo-2-kinase (PFKFB3) with IC50 of 207 nM. | ||
| M6340 | 3PO | PFKFB3 |
| 3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one | ||
| 3PO is a novel small-molecule inhibitor of the PFKFB3 isozyme, attenuates the proliferation of several human malignant hematopoietic and adenocarcinoma cell lines with IC50 of 1.4-24 μM. | ||
| M6727 | PFK-158 | PFKFB3 |
| ACT-PFK-158 | ||
| PFK-158, also known as ACT-PFK-158, is a potent and selective inhibitor of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases (PFK-2/FBPase) isoform 3 (PFKFB3) with potential antineoplastic activity. | ||
| M31413 | AZ-67 | PFKFB3 |
| AZ-67 is an inhibitor of PFKFB3 as well as glycolysis and can be used in studies related to neurodegenerative diseases. | ||
| M45095 | 5MPN | Phosphatase |
| 5MPN is a first-in-class, orally active and selective inhibitor of fructose-6-phosphate-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4), which does not inhibit PFK-1 or PFKFB3. 5MPN is a competitive inhibitor of the F6P-binding site (Ki=8.6 μM). 5MPN inhibits proliferation of various cancer cell lines by targeting tumor glucose metabolism. 5MPN is a competitive inhibitor of the F6P binding site (Ki=8.6 μM). 5MPN can inhibit the proliferation of various cancer cell lines by targeting tumor glycolysis. | ||
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