About 2 results found for searched term "PC14586" (0.127 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M11440 | PC14586 | p53 |
| PC14586 is the first-in-class oral small molecule p53 Y220C activator to enter the clinical phase, which induces the transformation of p53 protein from mutant to wild-type conformation in a dose-dependent manner. | ||
| M43013 | Rezatapopt | p53 |
| PC14586 | ||
| Rezatapopt is a first-in-class p53 reactivator that selectively binds to the mutated p53 Y220C protein and restores wild-type activity, used to inhibit solid tumor with p53 mutation. | ||
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