About 12 results found for searched term "PACA" (0.058 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M6136 | Epacadostat | IDO |
| INCB024360 | ||
| Epacadostat (INCB024360) is a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor with IC50 of 10 nM and displays high selectivity over other related enzymes such as IDO2 or tryptophan 2,3-dioxygenase (TDO). | ||
| M7098 | PACAP 1-27 | Others |
| PACAP 1-27 is a potent stimulator of adenylyl cyclase. | ||
| M8545 | PACA | Others |
| PACA is a potentiator of NGF-induced neurite outgrowth that attenuates 6-hydroxydopamine (6-OHDA) neurotoxicity in dopaminergic PC12 cells. | ||
| M10161 | PACAP (1-38) | Peptides |
| PACAP (1-38) is a highly potent PACAP receptor agonist (Kd = 100 pM), it stimulates adenylate cyclase and phagocytosis. | ||
| M25045 | Pacanalotamab | Others |
| AMG 420; BI-836909 | ||
| Pacanalotamab (AMG 420; BI-836909) is a bispecific T-cell engager (BiTE) targeting to BCMA and CD3ɛ. BCMA refers to B cell maturation antigen, as Pacanalotamab redirecting T cells to BCMA expressing cells on the cell surface. Pacanalotamab conducts T-cell redirected lysis of human multiple myeloma (MM) cell lines. | ||
| M51375 | PACAP-38 (28-38) (human, chicken, mouse, ovine, porcine, rat) | Others |
| PACAP-38 (28-38) (human, chicken, mouse, ovine, porcine, rat) is a polypeptide that can be found by peptide screening. | ||
| M52927 | PACAP (1-38) free acid | Others |
| PACAP (1-38) free acid is an endogenous neuropeptide. | ||
| M52928 | PACAP (6-38), human, ovine, rat | Others |
| PACAP (6-38), human, ovine, rat is a potent PACAP receptor antagonist with IC50s of 30, 600, and 40 nM for PACAP type I receptor, PACAP type II receptor VIP1, and PACAP type II receptor VIP2, respectively. | ||
| M52929 | PACAP-38 (16-38), human, mouse, rat | Others |
| PACAP-38 (16-38), human, mouse, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production. | ||
| M52930 | [Arg-15, 20, 21, Leu17]-PACAP-Gly-Lys-Arg-NH2 | Others |
| [Arg-15,-20,-21,Leu17]-PACAP-Gly-Lys-Arg-NH2 (BM-PACAP) is a synthetic PACAP 1-27 analogue with relaxant effect. | ||
| M53285 | PACAP (6-27) (human, ovine, rat) | Adenylate Cyclase |
| PACAP (6-27) (human, ovine, rat) is a PACAP receptor antagonist that blocks the canine adrenal catecholamine response to exogenous vasoactive intestinal peptide (VIP). | ||
| M54220 | PACAP-38 (31-38), human, mouse, rat | ERK |
| PACAP-38 (31-38), human, mouse, rat is a PAC1 receptor activator and increases the α-secretase activity. | ||
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