About 2 results found for searched term "PA-8 " (0.121 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M28881 | Mc-VC-PAB-SN38 | Drug-Linker Conjugates for ADC |
| Mc-VC-PAB-SN38 consists a cleavable ADC linker (Mc-VC-PAB) and a DNA topoisomerase I inhibitor (SN38). Mc-VC-PAB-SN38 can be used in the synthesis of antibody-drug conjugates (ADCs). | ||
| M30790 | PA-8 | Others |
| PA-8 is a potent, selective and orally active PACAP type I (PAC1) receptor antagonist. PA-8 inhibits the phosphorylation of CREB induced by PACAP in PAC1-, but not VPAC1- or VPAC2-receptor. PA-8 also inhibits PACAP-induced cAMP elevation with an IC50 of 2 nM. | ||
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