About 4 results found for searched term "P2X3-IN-1" (0.123 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M42220 | P2X3-IN-1 | P2 Receptor |
| P2X3-IN-1 is an inhibitor of P2X3 receptor. | ||
| M2954 | PPADS Tetrasodium | P2 Receptor |
| PPADS tetrasodium salt is a non-selective P2 purinergic antagonist blocking recombinant P2X1, P2X2, P2X3, P2X5 with IC50 of 1-2.6 μM, native P2Y2-like with IC50 of ~ 0.9 mM, and recombinant P2Y4 receptors with IC50 of ~ 15 mM | ||
| M29500 | Gefapixant citrate | P2 Receptor |
| MK-7264 citrate; AF-219 citrate | ||
| Gefapixant citrate is an orally active and potent purinergic P2X3 receptor (P2X3R) antagonist, with IC50 values of ~30 nM versus recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors. Gefapixant citrate can be used for the research of chronic cough and knee osteoarthritis. | ||
| M56548 | NF110 | P2 Receptor |
| NF110 is a P2X3 receptor antagonist (Ki = 36 nM) and inactive toward P2Y receptors stably expressed (IC50s > 10 M). | ||
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